Searchable abstracts of presentations at key conferences in endocrinology

ea0098b3 | Basic Science | NANETS2023

Translational biomarkers in G2-3 NENs: Analysis from NET-001 and NET-002 trials

Nunez Jose E. , Bruce Jeffrey , Danesh Arnavaz , Chan David L. , Rodriguez-Freixinos Victor , Hallet Julie , Myrehaug Sten , Law Calvin , Pugh Trevor , Singh Simron

Background: The treatment of neuroendocrine neoplasms (NENs) of higher grade remains a dilemma. In these patients the role of immunotherapy is still unclear and predictive biomarkers are an unmet need. Herein, we present a revised translational analysis of the NET001 and NET002 (NCT03278405, NCT03278379) clinical trials.Methods: Patients with advanced WHO G2-3 NENs who had a gastroenteropancreatic (GEP) or a bronchial primary (excluding typical carcinoid...